Abstract
Plasma-sprayed HA-coatings used for orthopaedic surgery can contain different percentages of crystalline phase. The influence of the amount of crystalline and amorphous phase on the biological properties of coatings is not known. The aim of this study is to determine the effect of this coating characteristic on mammalian cell functions in vitro. It appears that 100% crystalline coatings have an inhibiting effect on cell proliferation and on alkaline phosphatase activity. A direct contact of the cells with the material is necessary to obtain this effect. The material evolves during the period of culture. Poorly crystalline coatings dissolve during the period of culture and the roughness parameters change during the same period.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Journal of Materials Science: Materials in Medicine
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
