Abstract
Background: As malaria is still an important life-threatening infection in many tropical countries and drug resistance has become increasingly common to drugs used nowadays, there is a pressing need to find more drugs that may contribute to the reduction of malaria in the future. This calls for an inward look into harnessing the full potential of medicinal plants that abound around us. Objective: To evaluate the antiplasmodial activity of aqueous leaf and root extracts of Cymbopogon citratus against Plasmodium berghei in mice. Materials and Methods: Cymbopogon citratus extracts of 200, 400, 800 mg/kg, and 5 mg/kg of chloroquine were used. Antiplasmodial activity of the extracts was evaluated using 4-day suppressive test model. Results: The extracts exhibited significant (P Conclusion: The results of the study suggested that the aqueous root extract possesses a better antiplasmodial activity than the aqueous leaf extract.
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