Abstract
Introduction: Mucuna pruriens is a tropical legume native to Africa and tropical Asia. The plant is an annual climbing shrub with long vines that can reach a height of 15 meters in length. Mucuna pruriens belong to the family legume. It is a herbal drug that is used as a medicine for the treatment of male infertility, nervous disorder, and also as an aphrodisiac. It has been shown that it potentially has more medical importance. It causes orange hair that causes a severe itch when in contact with the skin. It releases a protein called mucanain.
 Aim: To determine the anti-inflammatory activity of aqueous and hexane extract of Mucuna pruriens.
 Materials and Methodology: The extract was prepared and the anti-inflammatory effect was done using a UV-Beckmann spectrometer. The anti-inflammatory activity of nanoparticles prepared using plant extract was investigated by albumin denaturation assay. The results of the test were described as the standard deviation and analyzed using UV-Vis spectroscopy. Correlation and analysis were done in SPSS.
 Results: The hexane solution and aqueous solution of Mucuna pruriens have a high percentage of inhibition at the 30 μl, 40 μl and 50 μl concentration when compared with a standard solution. And hexane has a high percentage of inhibition at 50μl when compared with a standard solution. The obtained data were analyzed using spearman correlation analysis and the non-parametric correlation was statistically significant at p value< 0.05.
 Conclusion: The aqueous and hexane extract of Mucuna pruriens show good anti- inflammatory activity. In that hexane extract has good anti-inflammatory activity when compared with aqueous extract. And it is used for disease. And further research should be done with the action and mechanism of Mucuna pruriens.
Highlights
Mucuna pruriens is a tropical legume native to Africa and tropical Asia
The hexane solution and aqueous solution of Mucuna pruriens have a high percentage of inhibition at the 30 μl, 40 μl and 50 μl concentration when compared with a standard solution
In that hexane extract has good anti-inflammatory activity when compared with aqueous extract
Summary
Mucuna pruriens is a tropical legume native to Africa and tropical Asia. The plant is an annual climbing shrub with long vines that can reach a height of 15 meters in length. Mucuna pruriens belong to the family legume. It causes orange hair that causes a severe itch when in contact with the skin Aim: To determine the anti-inflammatory activity of aqueous and hexane extract of Mucuna pruriens. Mucuna pruriens belong to the legume family and it is a flavourer drug used for the treatment of male sterility, nervous disorders, and as an aphrodisiac. The pods or legumes are bushy, thick, and leatherlike, average it's four inches long, and has formed like string sound holes, and contains seeds. They are brown with thick coats and stiff hairs [2]. Emulsifiers are proteins found in living things that are capable of interacting with carbohydrates [3,4]
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