Antioxidant and Antiinflammatory Activity of Titanium Dioxide Nanoparticles Synthesised Using Mucuna pruriens

Abstract

Introduction: The genus Mucuna, belonging to the Fabaceae family, sub family Papilionaceae, includes approximately 150 species of annual and perennial legumes. Titanium dioxide (TiO2) nanoparticles (NPs) are manufactured worldwide in large quantities for use in a wide range of applications.Various studies have been done in this topic like determining the efficacies of antibacterial and antioxidant activities of aqueous leaf extract of Psidium guajava mediated biosynthesis of titanium dioxide nanoparticles. Other studies have suggested that Obtaining biopeptides by enzymatic hydrolysis adds value to proteins of vegetative origin, such as Mucuna pruriens L. Thus it evaluated the effect of enzymatic digestion of protein derivatives obtained from M. pruriens L. Although a lot of studies have been done on Titanium dioxide nanoparticles and its various activities like anti-inflammatory, antioxidant and anti diabetic, there are not many studies in the area of checking anti inflammatory and antioxidant activity of titanium dioxide nanoparticles synthesised using Mucuna pruriens The aim of this study is to observe the antioxidant and anti inflammatory activity of Titanium dioxide nanoparticles synthesised using Mucuna pruriens.
 Materials and Methods: A titanium dioxide nanoparticle is synthesised using Mucuna pruriens, extract used to perform albumin denaturation assays and DPPH method, where % zone of inhibition increases as the concentration of nanoparticles increases.
 Results: The Mucuna pruriens medicated titanium dioxide nanoparticle has positive antioxidant and anti-inflammatory properties.
 Conclusion: The present study concluded that Mucuna pruriens mediated copper nanoparticle has good antioxidant and anti-inflammatory activity at its high concentration which is nearer to that of the standard drugs.