Comparative analysis of the quantitative parameter method and elasticity color mode method for real-time shear wave elastography in the diagnosis of benign and malignant solid breast lesions.

Shan-Shan Xue,Wei Sheng,Fei-Qian Wang,Qiao-Ling Zhao,Li-Tao Ruan,Can Zhou

doi:10.1177/03008916211048239

Shan-Shan Xue, Wei Sheng + Show 4 more

Open Access

https://doi.org/10.1177/03008916211048239

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Abstract

To examine the performance of real-time shear wave elastography (RT-SWE) in routine clinical practice. This was a prospective study of 500 patients. The elasticity color mode method was judged by a four-mode system. The quantitative parameter method was used to measure the modulus of elasticity of the lesions. Pathologic reports were used as a gold standard to comparatively analyze the diagnostic performance of the two methods. A total of 553 tumors were detected. The average mode value and the modulus of elasticity (Emax) of the benign breast masses was lower than that of malignant masses (p < 0.05). With Emax = 67.4 as the diagnostic threshold value, the sensitivity, specificity, accuracy, negative predictive value, and positive predictive value of the two methods were not statistically significant different (p > 0.05). The shear wave quantitative parameter method and the elasticity color mode method showed similar performances in the diagnosis of benign and malignant breast masses. The elasticity color mode method is convenient and intuitive, whereas the quantitative parameter method can be used to objectively assess the lesions when it is difficult to score the elasticity of an image, but could not be relied on alone.

Highlights

As stated by Horodecki et al [1], it was Einstein, Podolsky, and Rosen (EPR) and Schrödinger who first recognized a “spooky” feature of quantum machinery which lies at the center of interest of physics of the 21st century“ [2,3]
Quantum entanglement is a phenomenon in theoretical physics that happens when pairs or groups of particles are generated in such a way that the quantum state of each particle cannot be described independently of the others – even when the particles are separated by a large distance
This was due to a stimulation of cell migration and proliferation of connective tissue fibroblasts

Summary

Introduction

As stated by Horodecki et al [1], it was Einstein, Podolsky, and Rosen (EPR) and Schrödinger who first recognized a “spooky” feature of quantum machinery which lies at the center of interest of physics of the 21st century“ [2,3]. It describes a physical phenomenon that occurs when a group of particles interact in such a way that the quantum state of each particle of this group cannot be described independently from the state of the others. This includes a state when the particles are separated by a long distance. The term for this phenomenon is called quantum entanglement and was originally called by Schrödinger et al as Verschränkung [46]. The intensive increase in energy that takes place is referred to as quantum physical product refinement. The quantum physical product refinement can be carried out over a longer distance by using the possibilities of 90.10. quantum entanglement

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