Abstract
The purpose of the study was to determine the effect of tricalcium silicate cement on the protective process of pulp in the treatment of reversible pulpitis. There was carried out an experiment on 3-month-old male rabbits to study morphofunctional changes in the pulp tissue with modeling of reversible pulpitis followed by vital amputation with coating of the pulp with tricalcium silicate (8 animals, study group) and mineral trioxide aggregate (MTA) (8 animals, comparison group). In 2 and 6 weeks dental tissues were fixed by 10% formalin solution and after decalcification and done routine procedures, histological sections were made, stained with hematoxylin and eosin. After the application of tricalcium silicate cement in 2 weeks, the odontoblast density changed to 3.92±1.03×103/mm2 from 8.3±1.02×103/mm2 of cell density in the intact group. The number of neutrophils also plays a big role in the regeneration of inflamed pulp. Thus, in 2 weeks the number of neutrophils made up 6.39±2.61x102 per 1 mm2, which is 3 times less than after mineral trioxide aggregate usage – 19.49±2.85x102per 1 mm2. It was established that the processes of rheological disorders with impaired lymph circulation are replaced by the restoration of the cellular component. In such a way the proposed vital amputation was examined for reversible pulpitis and it revealed similar clinical and pathological effectiveness with a positive regenerative process with formation of a sufficient number of odontoblasts (7.98±1.51×103/mm2) for the subsequent formation of a hard tissue bridge, which consists of collagen fibers in the form of a frame. The main goal of vital amputation procedure is regeneration (proliferation) of the pulp with a short-term signs of alteration and exudation, which is provided by the choice of material for the pulp covering. Thus, after the vital amputation of the pulp, followed by the use of tricalcium silicate cement 6 weeks after, the number of neutrophils was 1.39±0.72x102per 1 mm2, which is 5 times less than after using mineral trioxide aggregate.
Highlights
IntroductionКількість нейтрофілів через 2 тижні становила 6,39±2,61х102 на 1 мм, що в 3 рази менше, ніж після використання мінерал триоксид агрегату – 19,49±2,85х102 на 1 мм
Two weeks after the modeling of the reversible pulpitis in the pulp tissue there were found manifestations of protective-adaptive mechanisms in the form of the inflammatory process with its resolution, with necrosis zone being replaced by connective tissue
It was established that after tricalcium silicate (TCS) using in 6 weeks the number of neutrophils is 5 times less than after applying mineral trioxide aggregate (MTA) and revealed similar clinical and pathological efficacy with a positive regenerative process with the formation of a bridge of hard tissues, which consists of collagen fibers in the form of a frame
Summary
Кількість нейтрофілів через 2 тижні становила 6,39±2,61х102 на 1 мм, що в 3 рази менше, ніж після використання мінерал триоксид агрегату – 19,49±2,85х102 на 1 мм. Після вітальної ампутації пульпи з подальшим застосуванням трикальцій силікатного цементу через 6 тижнів кількість нейтрофілів становила 1,39±0,72х102 на 1 мм, що в 5 разів менше, ніж після використання мінерал триоксид агрегату. Long-term observations after treatment with calcium hydroxide-based drugs have shown that its effectiveness decreases with the increase of the observation period. All this has become a prerequisite for replacing calcium hydroxide with more modern materials, which are based on mineral trioxide aggregate. The aim of this study was to determine the effects of tricalcium silicate and mineral trioxide aggregate on the course of reversible pulpitis by detection of morpho-functional peculiarities of changes in the pulp tissue
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
