Comparative analysis of oral fluid metabolism parameters between patients with complicated and uncomplicated implantation

Abstract

ВACKGROUND: Modern scientific research continues to develop promising areas for diagnosing inflammatory complications after dental implantation. Analysis of studies shows that inflammatory complications depend on various factors, the establishment of which can be challenging. Hence, saliva diagnostics opens up broad prospects for studying the pathogenetic basis of the development of inflammatory processes. АIM: To study in a comparative aspect the metabolic status of complicated and uncomplicated implantation. MATERIALS AND METHODS: This study examined 88 patients (30 with peri-implant mucositis [main group I], 28 with uncomplicated implantation [comparison group II], and 30 controls [control group]) aged 45.3±2.4 years who were followed up for 1–3 years. RESULTS: Based on the results of the studies and comparative analysis of complicated and uncomplicated implantation, previously unknown data on their distinctive metabolic characteristics were obtained and presented. With complicated implantation, these include a characteristic increase in C-reactive protein, iron, and uric acid and a decrease in calcium levels. CONCLUSION: New information revealing prognostically significant factors of gastric cancer metabolism during complicated and uncomplicated implantation has been obtained. The identified changes in metabolism during implantation should be considered and differentiated from early metabolic signs of inflammation. The study of oral fluid is objective and promising in the diagnosis of the inflammatory process and its prognosis.