Comparative Analysis of Imidazole and Urtica dioica Emulsions in the Management of Dermatophytic Infections

Abstract

This study explores the epidemiological distribution and antifungal efficacy of treatments against common dermatophytic infections, which predominantly include species from the genera Trichophyton, Microsporum, and Epidermophyton. These infections are significant due to their prevalence and the challenge posed by recurrence and resistance. Between January and September 2022, 35 fungal samples were collected from a dermatological clinic and analyzed using various growth media. Our research focused on evaluating the antifungal effectiveness of a synthetic imidazole emulsion (CSI), an antibiotic, and a natural emulsion from Urtica dioica (CSP). Results revealed that CSI and antibiotic treatments were significantly more effective across all tested species compared to CSP, with CSI often showing superior or comparable efficacy to antibiotics. The findings underscore the robust antifungal properties of imidazole derivatives and suggest a potential limitation in the therapeutic utility of U. dioica extracts. The study highlights the need for continued exploration of innovative treatments and the development of effective management strategies for fungal infections, considering the variance in species prevalence and treatment response.