Abstract
BackgroundThere is evidence of the relation between obesity and an increase in prostate-specific antigen, albeit some is contradictory. AimsOur aim was to compare prostate-specific antigen values in patients with and without abdominal obesity that were seen at the urology service of a tertiary care medical unit, and to analyze the results. Material and methodsA cross-sectional analytic study was conducted within the time frame of June to October 2014. It included first-time urology consultation patients that were referred due to presenting with prostate disease and that had not received medication modifying prostate-specific antigen values. Waist circumference and serum prostate-specific antigen levels were measured. The Student's t test was used for the independent samples and the Pearson and Spearman correlations and the Mann-Whitney U test were used to evaluate the correlation between waist circumference and prostate-specific antigen levels. ResultsA total of 110 patients were included that were first-time referrals to the urology service due to prostate pathology. Calculated as means, patient age was 62.6±7.5 years (range: 48-79), waist circumference was 104.5±10.6cm (range: 57-130), and prostate-specific antigen level was 3.4±2.5ng/dl (range: 0.46-21). The mean prostate-specific antigen level was 1.2±6.3ng/dl (range: 0.46-10.0) for the patients with obesity and 0.4±1.9ng/dl (range: 1.21-21) for the patients without obesity. ConclusionThere was no statistically significant difference in prostate-specific antigen values in the comparison of the populations presenting with and without obesity.
Published Version
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