Abstract
This study explored physical and psychiatric comorbidities of mood disorders using association rule mining. There were 7709 subjects who were patients (19 years old) diagnosed with mood disorders and included in the data collected by the Korean National Hospital Discharge In-depth Injury Survey (KNHDS) between 2006 and 2018. Physical comorbidities (46.17%) were higher than that of psychiatric comorbidities (27.28%). The frequent comorbidities of mood disorders (F30–F39) were hypertensive diseases (I10–I15), neurotic, stress-related and somatoform disorders (F40–F48), diabetes mellitus (E10–E14), and diseases of esophagus, stomach, and duodenum (K20–K31). The bidirectional association path of mood disorders (F30–F39) with hypertensive diseases (I10–I15) and diabetes mellitus (E10–E14) were the strongest. Depressive episodes (F32) and recurrent depressive disorders (F33) revealed strong bidirectional association paths with other degenerative diseases of the nervous system (G30-G32) and organic, including symptomatic and mental disorders (F00–F09). Bipolar affective disorders (F31) revealed strong bidirectional association paths with diabetes mellitus (E10–E14) and hypertensive diseases (I10–I15). It was found that different physical and psychiatric disorders are comorbid according to the sub-classification of mood disorders. Understanding the comorbidity patterns of major comorbidities for each mood disorder can assist mental health providers in treating and managing patients with mood disorders.
Highlights
Mood disorders, including depressive disorders and bipolar disorders, are common mental disorders in mental health practice
The prevalence rate of psychiatric comorbidity was in the order of others (50.00%), Medicaid II (34.31%), Medicaid I (31.35%), and National health (26.48%) (p < 0.001)
The patterns of comorbidities in patients with mood disorders were evaluated using ARM based on clinical data, and it was found that different physical and psychiatric disorders comorbid each sub-diagnosis of mood disorders
Summary
Mood disorders, including depressive disorders and bipolar disorders, are common mental disorders in mental health practice. Depressive disorders are one of the major causes of the years lived with disability. Mood disorders are a mental disorder type that burdens individuals and society highly. The research analyzed the health insurance claims of mood disorders (F30–F39) from 2016 to 2020 using the medical data of the National Health Service of South Korea and reported that the number of patients with mood disorders increased by 6.9% annually on average [4]. The majority of mental disorder patients are hospitalized due to mood disorders [5]. In South Korea, the total health insurance of claims due to mood disorders increased by 57.2% (KRW 245.9 billion) over five years from KRW 429.9 billion in 2016 to KRW 675.7 billion in 2020, with an average annual increase rate of 12.0% [4]
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