Comorbidity as a factor initiating a shift in the microelement composition of saliva

Abstract

The comorbidity of diseases reflects the mutual influence of pathological conditions of individual organs and systems of the body, which requires taking into account the current state of the patient. The presence of comorbidity in modern dentistry is one of the important problems that require attention in diagnosing a patient's condition, selecting treatment tactics and predicting the results of interventions. The possibility of diagnosing concomitant diseases by changing the microelement composition of saliva makes it possible to more effectively determine their presence, the severity of the existing concomitant pathology and determine the optimal treatment tactics.Trace elements contained in saliva regulate a number of biological processes, and their level reflects the state of homeostasis of the oral cavity, and in systemic diseases, the composition of saliva has a strong correlation with blood plasma and, therefore, can reflect the state of health of the body.There are both comorbidity of exclusively dental pathology, and comorbidity of dental diseases with other somatic pathologies. At the same time, the determination of changes in the microelement composition of saliva may indicate the development of inflammatory processes both in the oral cavity and in the body as a whole, a decrease in antioxidant protection, damage to enzyme systems and ion channels, pathological changes in mucous membranes, etc. . The possibility of analyzing the microelement composition of saliva in assessing the comorbidity of a patient's comorbidities seems to be a promising area of research in modern dentistry.