Abstract
Aims. Based on the data of the Register of new cases of pulmonary arterial thromboembolism (PE) in Tomsk hospitals (2003–2012), to study the development of thromboembolism in patients with atrial fibrillation (AF). Results. The database of the Register of new cases of hospital PE included data from patients with PE (751 people) who died in the city’s hospitals and underwent autopsy. Among them, 238 patients were identified who had AF before the development of PE (in 185 patients — a permanent form of AF, in 53 — paroxysmal and persistent). Among metabolic disorders, 25% of patients showed obesity of various degrees and 27% had type 2 diabetes. Chronic heart failure 2 stages in the phase of decompensation was diagnosed in 41% of patients. The number of verified cases of PE in persons with AF did not differ significantly from patients without fibrillation and was 40%. According to autopsy data, pulmonary embolism is recognized as the main cause of death in more than half of people with AF (in 131 cases). A massive volume of pulmonary artery disease was detected in 109 patients with AF (46%). Among patients with thromboembolism from the right heart chambers, AF as a whole (regardless of form) was found in 56% of cases, that is, significantly more often than in patients with a source of embolism in the inferior vena cava (14.3%, p=0.005), veins of the lower limbs (27%, p<0.001) and veins of the pelvis (2.6%, p=0.014). Similar relationships were found in persons with chronic AF. For the paroxysmal form of differences between groups with different sources of embolism, it was not possible to identify. According to autopsy data, in patients with atrial fibrillation, the right heart was the source of PE in 121 patients (48%), 85% of them in the right atrial appendage.
Highlights
atrial fibrillation associated with pulmonary embolism
Сведения об авторахВорожцова Ирина Николаевна, д-р мед. наук, профессор, ведущий научный сотрудник отделения ультразвуковой и функциональной диагностики Научно-исследовательского института кардиологии, Томский национальный исследовательский медицинский центр Российской академии наук; заведующая кафедрой эндокринологии и диабетологии Сибирского государственного медицинского университета Министерства здравоохранения Российской Федерации
Summary
В дальнейшем, после развития ТЭЛА, ФП выявлялась у 14% лиц, составив, таким образом, за время исследования в целом 32,1% случаев при средней продолжительности наблюдения 5,0±3,7 года. Этим обусловлено и отсутствие четкого представления в отношении распространенности тромбоза правого предсердия и правого желудочка в целом, независимо от ритма сердца, а также связанных с тромботическими процессами в правых камерах рисков развития легочной эмболии. При этом распространенность легочной эмболии у лиц с изолированным внутрисердечным тромбозом левых камер сердца, изолированным внутрисердечным тромбозом правых камер сердца и сочетанным внутрисердечным тромбозом составила 28,5, 35,6 и 48,9%, соответственно. Томска (2003–2012 гг.) изучить условия развития тромбоэмболии у пациентов с ФП
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
