Abstract
Commingle Consumption of Monosodium Glutamate and Aspartame and Potential Reproductive System Affection of Female Albino Rats: Involvement of VASA Gene Expression and Oxidative Stress
Highlights
Evaluating the safe consumption of food additives is commonly accepted after testing their toxicities through animal studies as there is scarce data from human studies
Subchronic exposure to individual monosodium glutamate and ASP noteworthy increased body weight after repeated oral administration for 30 days. This result was similar to Oluba et al (2011), who found that all Monosodium glutamate (MSG) treated groups gained weight. This boosts the fact reported by Samuels (1999) that monosodium glutamate ingestion gives rise to an increase in the food zest which leads to increased body weight and adiposity
These findings were near to Miskowiak and Partyka (1993) who documented a decrease in weight of pituitary glands when the dose of MSG (4 mg/g) was administered to newborn rats
Summary
Evaluating the safe consumption of food additives is commonly accepted after testing their toxicities through animal studies as there is scarce data from human studies. The main aim of animal studies is to evaluate the May 2021 | Volume 9 | Issue 5 | Page 700 additives’ potential risks for human toxicity and to establish the conditions for safe use (Lin et al, 1992). Monosodium glutamate is considered one of the commonly used flavors all over the world. It exists in numerous assortments of different foods (Rim, 2017; Bojanić et al, 2009). Fears have increased because of the toxic effects of MSG, with minimal research about the cytotoxic damage of ovaries with MSG exposure as its effects on the reproductive system were out of the scope of most previous studies (Husarova and Ostatnikova, 2013)
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
