Commentary on: The Effect of Lipoaspirates on Human Keratinocytes.

Abstract

There is no doubt that the “old” lipoaspirate continues to surprise. It once became the basis of the autologous fat grafting technique, and it seems to play a major role in what today is called regenerative surgery. With an aging population and a higher incidence of degenerative diseases, treatments based on pharmacological approaches, radiotherapy, and surgery often fail to restore the optimal tissue condition that is normally found in young people. Only a rejuvenating/regenerating treatment can achieve this effect, and this treatment appears to be linked to the possibility of donating stem cells to tissue that has lost them. Regenerative surgery, born in the nineties, often exploits the huge potential of stem cells. In fact, stem cells have an anti-inflammatory, immunomodulatory, anti-fibrotic, and pro-angiogenic effect. Plastic surgery has taken advantage of this knowledge by quickly identifying in adipose tissue a prominent source of stem cells that can be used either directly in the operating room …