Commentary: Lack of functional specialization of neurons in the mouse primary visual cortex that have expressed calretinin.

Filip Barinka

doi:10.3389/fnins.2016.00230

Abstract

Commentary: Lack of functional specialization of neurons in the mouse primary visual cortex that have expressed calretinin.

Highlights

The intracellular protein calretinin (CR) is frequently used as a marker of specific cortical interneuronal population
We still lack precise data about the physiological roles of calretinin in neocortical neurons and we do not know whether the presence of calretinin protein in these neurons is directly coupled to any special physiological feature of these cells
Alexander Heimel from the Netherlands Institute for Neuroscience with his research group decided to challenge this topic by characterizing the physiological response properties of CR+ interneurons in the primary visual cortex of the mouse in vivo (Camillo et al, 2014)

Summary

Introduction

The intracellular protein calretinin (CR) is frequently used as a marker of specific (albeit heterogeneous) cortical interneuronal population (see Cauli et al, 2014; Schwaller, 2014 for recent reviews). Lack of functional specialization of neurons in the mouse primary visual cortex that have expressed calretinin By Camillo, D., Levelt, C. Alexander Heimel from the Netherlands Institute for Neuroscience with his research group decided to challenge this topic by characterizing the physiological response properties of CR+ interneurons in the primary visual cortex of the mouse in vivo (Camillo et al, 2014).

Results

Conclusion