Abstract
Commentary: GABA Depolarizes Immature Neurons and Inhibits Network Activity in the Neonatal Neocortex In vivo.
Highlights
Specialty section: This article was submitted to Neuropharmacology, a section of the journal Frontiers in Pharmacology
Based almost exclusively on the in vitro studies (Zilberter et al, 2010; Bregestovski and Bernard, 2012), extrapolations have leads to the theory of excitatory-toinhibitory switch of GABA action and its central role in brain maturation (Ben-Ari et al, 2007, 2012)
In anesthetized P3-4 mice, Kirmse and colleges first showed that GABA application induced a dramatic, 16-fold drop in cortical plate (CP) cell membrane resistance
Summary
Specialty section: This article was submitted to Neuropharmacology, a section of the journal Frontiers in Pharmacology. A commentary on GABA depolarizes immature neurons and inhibits network activity in the neonatal neocortex in vivo by Kirmse, K., Kummer, M., Kovalchuk, Y., Witte, O. Depolarizes Immature Neurons and Inhibits Network Activity in the Neonatal Neocortex In vivo.
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