Abstract
Commentary: Blurring Borders: Innate Immunity with Adaptive Features.
Highlights
Laboratory of Comparative Immunology, Department of Neurobiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA
Removed from the pervasive T and B cell paradigm putative Natural killer (NK) cells function in complex invertebrates
Recipients of sensitized coelomocytes reject test grafts more rapidly than controls, shorter than earthworms injected with leukocytes from unsensitized worms (Bailey et al, 1971)
Summary
A commentary on Blurring Borders: Innate Immunity with Adaptive Features by Kvell, K., Cooper, E. Expanding the repertoire of invertebrate innate immunity has greatly facilitated a search for what constitutes innate and adaptive. Strict definitions become blurred casting skepticism on using rigid definitions that define innate and adaptive immunity (Kvell et al, 2007). We can even include features of adaptive responses especially to danger (Pradeu and Cooper, 2012).
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