Comment on "Malnutrition in Relation to Muscle Mass, Muscle Quality, and Muscle Strength in Hospitalized Older Adults".

Abstract

In a recent JAMDA article, Xie et al 1 Xie L. Jiang J. Fu H. et al. Malnutrition in relation to muscle mass, muscle quality, and muscle strength in hospitalized older adults. J Am Med Dir Assoc. 2022; 23: 714-720 Google Scholar reported that patients with a malnutrition diagnosis assessed by the Global Leadership Initiative on Malnutrition (GLIM) had significantly lower skeletal muscle radiodensity, an indicator of muscle quality, and lower handgrip strength in both genders. Additionally, women, but not men, with a malnutrition diagnosis had significantly higher intermuscular adipose tissue (IMAT), another indicator of muscle quality, than women with normal nutrition; moreover, in contrast to women, men with malnutrition had significantly lower skeletal muscle index (SMI), an indicator of muscle mass. In contrast to SMI, skeletal muscle radiodensity and handgrip strength, IMAT was not associated with malnutrition. Response to the Comments on “Malnutrition in Relation to Muscle Mass, Muscle Quality, and Muscle Strength in Hospitalized Older Adults”Journal of the American Medical Directors AssociationVol. 23Issue 5PreviewWe thank Drs Tasci and Naharci for their interest in our recent manuscript.1 First, according to the Global Leadership Initiative on Malnutrition (GLIM) consensus, the diagnosis of malnutrition should include at least 1 phenotypic criterion (either weight loss, low body mass index, or “reduced muscle mass”) and 1 etiologic criterion (either reduced food intake, assimilation disease burden, or inflammatory condition).2 In our study, we defined malnutrition based on this algorithm. However, we did not include reduced muscle mass as a phenotypic criterion to define malnutrition because one of our aims was to explore the association between malnutrition and muscle mass. Full-Text PDF