Abstract

Background and Aims : In-vivo imaging techniques like optical coherence tomography (OCT) can be used in patients to characterize lipid presence in atherosclerotic plaques (i.e. lipid-rich arteries). However, they do not provide detailed information on plaque lipid composition and distribution. The aim of this study was to identify, characterize and visualize distribution of lipids using MALDI-MSI in the regions that OCT detected as lipid-rich in swine atherosclerotic plaques.

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