Abstract
The aim of our study was to determine epidemiological, clinical and therapeutic profile of colorectal cancers in Mauritania. Patients and Methods: It was a retrospective multicentric study conducted over 5 years in Nouakchott National Hospital Centre and in private clinics of Mauritania. All cases of colorectal cancers histologically confirmed were included. The Astler and Coller classification was used to classify lesions by level of extension. Results: 225 patients were included with a sex ratio (M/F) of 1.39, an average age of 52.3 years. Location of the lesion was rectal (37.7%) and colonic (62.3%). Clinical manifestations were dominated by rectal bleeding (26.9%), occlusive syndrome (16.5%) and transit disorders (11.6%). Endoscopic lesions were of stenosing (45.2%), ulcero-burgeoning (39%), ulcerous (7.5%) and burgeoning (4.7%) types. Histological profiles were adenocarcinoma (88.9%), carcinoma (3.1%) and lymphoma (2.6%). The work-up for extension revealed metastasis in 33.6% of cases. These were stage B (49%) and C (36%) among the 95 cancers that received the Astler and Coller classification. The treatment was curative (80.83%) and palliative (19.16%). Conclusion: Colorectal cancer is a reality in Africa. However, its diagnosis still remains delayed, which increases the prognosis, hence the need to promote screening tests.
Highlights
At global level, colorectal cancer (CRC) is the most common digestive cancer [1]
Patients and Methods: It was a retrospective multicentric study conducted over 5 years in Nouakchott National Hospital Centre and in private clinics of Mauritania
Clinical manifestations were dominated by rectal bleeding (26.9%), occlusive syndrome (16.5%) and transit disorders (11.6%)
Summary
In Africa, colorectal cancer data are mainly derived from endoscopic and surgical series. This is a male ailment between 45 and 60 years [4]. In Sub-Saharan Africa, adenocarcinoma of Lieberkünien type is the predominant histological type in over 97% of cases [6] [7] [8]. The prognosis remains poor with a low 5-year survival [5]. The aim of this Senegalese-Mauritanian study was to determine epidemiological, clinical and therapeutic profile of colorectal cancer in Mauritania, a buffer country between the Maghreb and Black Africa
Sign-in/Register to view highlights & summary 
Published Version (
Free)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
