Abstract

Colorectal cancer is a major cause of morbidity and mortality throughout the world. There is no study about colorectal cancer in our country. The aim of the study was to assess epidemiological, clinical, therapeutic and histological aspects of colorectal cancer over a 10-year period (1999-2008) in Kamenge university hospital, Bujumbura, Burundi, by a descriptive retrospective study. A total of 37 cases of colorectal cancer, 22 males (59.5%) and 15 females (40.5%), mean age 50.8 years, were retrieved over the period of the study. The colorectal cancer was revealed by a rectal bleeding in 21 patients (56.8%) and an occlusive syndrome in 5 patients (13.5%). All patients underwent surgery. According to Dukes’ stages: 27% were A, 27% B, 19% C and 27% stage D. Histopathologically, 18 cases (46.7%) were differentiated adenocarcinoma, 14 cases (37.8%) undifferentiated adenocarcinoma, 2 cases of lymphoma and 2 cases of leiomyosarcoma. All patients underwent surgery. The hospitalization stay was a mean of 27 days. The prognosis was poor with a mortality rate of 13.5% in the hospital. In conclusion, colorectal cancer deserves awareness as a public health problem in our country.

Highlights

  • Colorectal cancer (CRC) is a major cause of morbidity and mortality throughout the world [1]

  • In striking contrast to the situation in the Western world, CRC seems to be rare among the population in Sub-Saharan Africa

  • Proportions are given with their confidence interval 95% (CI); p value < 0.05 was considered as statistically significant

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Summary

Introduction

Colorectal cancer (CRC) is a major cause of morbidity and mortality throughout the world [1]. CRC is the third most common cancer. (2016) Colorectal Cancer: Epidemiological, Clinical and Histopathological Aspects in Burundi. As people continue to live longer, CRC will become an even greater public health problem worldwide. In Burundi, CRC would be the 3rd digestive cancer after gastric and liver cancers, according to a small study in 1990 [8]. No study has been carried out about epidemiological, clinical and histological aspects of CRC in our country. The aim of our study was to evaluate epidemiological, clinical, therapeutic and histological aspects of CRC over a 10-year period (1999-2008) in Kamenge university hospital, Bujumbura, Burundi

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