Abstract

Purpose. Evaluation of feasibility of colon capsule endoscopy (CCE), as non-invasive method of diagnostics of colon abnormalities. Patients and methods. From 31.01.2014 to 10.01.2017 we successfully performed 100 CCE in 101 (99,0%) patients (m-50, f-48, mean age 44,7 ± 14,8 years, range 22–81), including 2 twins aged 8 years (CCE was performed with pediatrician). The main indication for colonoscopy was colorectal cancer screening (73 (73,0%) pts). The indication for colonoscopy to 2 twins was complicated Peutz Jeghers syndrome in one of them. CCE was performed using the system PillCam (Given Imaging) and capsule PillCam Colon 2. For the bowel preparation we used two-stage regimen; for the evaluation of preparation — J.A. Leighton scale. Results. Preparation was adequate in 88 (88,0%) pts, non-adequate — in 12 (12,0%) pts. Total CCE was performed in 82 (82,0%) patients. The mean colon transit time was 4 hours 43 min ± 3 hours15 min. Total evaluation of the colon was performed in 82 (82,0%) pts. Mucosal lesions were revealed in 75 (75,0%) pts, including epithelial polyps in 52 (69,3%) pts. We also revealed comorbid lesions in 41 (54,6%) pts. Colonoscopy after CCE was recommended to 28 (37,3%) pts because of polyp detection, sized ≥6 mm, and because of inflammatory changes of colon mucosa, but only 11 (39,3%) pts were performed colonoscopy. Conclusion. In this article the experience of colon capsule endoscopy demonstrates the principal possibility of noninvasive evaluation of the colon and detection of colon abnormalities.

Highlights

  • Колоноскопия является стандартной методикой осмотра толстой кишки

  • From 31.01.2014 to 10.01.2017 we successfully performed 100 colon capsule endoscopy (CCE) in 101 (99,0%) patients (m-50, f-48, mean age 44,7 ± 14,8 years, range 22–81), including 2 twins aged 8 years (CCE was performed with pediatrician)

  • We revealed comorbid lesions in 41 (54,6%) pts

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Summary

ИССЛЕДОВАНИЯ И ПРАКТИКА В МЕДИЦИНЕ

Изучение возможностей видеокапсульной колоноскопии (ВКК) в диагностике заболеваний толстой кишки. Показанием к проведению ВКК послужило исследование толстой кишки преимущественно с целью скрининга (73 (73,0%) пациентов). Тотальный осмотр толстой кишки с помощью видеокапсулы был осуществлен у 82 (82,0%) из 100 пациентов. Колоноскопия после ВКК была рекомендована 28 (37,3%) пациентам по причине выявления эпителиальных образований размером ≥6 мм и воспалительных изменений слизистой оболочки толстой кишки, однако только 11 (39,3%) пациентов явились для ее выполнения. Представленный опыт выполнения колоноскопии с помощью видеокапсулы демонстрирует принципиальную возможность полноценной визуализации толстой кишки и диагностики заболеваний органа малоинвазивным путем. Колоноскопия с помощью видеокапсулы: возможности неинвазивной диагностики заболеваний толстой кишки. Lobachevskogo, Moscow 119415, Russia; 3 Lomonosov Moscow State University, 27-1 Lomonosovskyi prospect, Moscow 119192, Russia; 4 “Klinika-A”, 4 Platanovyi bul’var, Krasnodar 350089, Russia; 5 Morozov Pediatric City Clinical Hospital, Department of Health in Moscow, 1-9 4th Dobrininskyi pereulok, Moscow 119049, Russia

ПАЦИЕНТЫ И МЕТОДЫ
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РЕЗУЛЬТАТЫ ИССЛЕДОВАНИЯ

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