Abstract
s1 November 1965Colloid Concentration and Albumin Synthesis.Marcus A. Rothschild, M.D., F.A.C.P., Murray Oratz, Ph.D., Sidney S. Schreiber, M.D., F.A.C.P.Marcus A. Rothschild, M.D., F.A.C.P.Search for more papers by this author, Murray Oratz, Ph.D.Search for more papers by this author, Sidney S. Schreiber, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-63-5-915_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn the presence of hypergammaglobulinemia, and after the administration of gamma globulin and dextran, albumin levels decrease due to a decrease in albumin production. The extravascular albumin pool is conserved. However, in the presence of cortisone and following the administration of thyroid, albumin synthesis increases with a decrease in the extravascular albumin pool. These observations coupled with the oft observed reciprocal changes in albumin and globulin levels in the serum suggested the presence of a colloid osmotic regulatory system affecting control of albumin production and also that such a system might be located in an extravascular site. Albumin metabolism and... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, New York PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 November 1965Volume 63, Issue 5Page: 915-915KeywordsAlbuminsAttentionDextranGlobulinsHypergammaglobulinemiaSerum albuminThyroid Issue Published: 1 November 1965 PDF downloadLoading ...
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