Abstract
Electrospinning technology was employed to fabricate a novel composite membrane integrating collagen from Peruvian squid skin with polystyrene (PS), polycaprolactone (PCL), and green-synthesized nickel oxide (NiO) nanoparticles (PS/PCL/CO/NiO). The addition of collagen (CO) and NiO nanoparticles significantly enhanced the membrane’s hydrophobicity, as evidenced by an increase in the water contact angle from 124.8±0.6° to 131.2±1.2°. Mechanical properties showed substantial improvement, with tensile strength increasing by 86% (from 5.05±1.6 MPa to 9.39±1.4 MPa) and elongation at break improving by 48% compared to conventional NiO membranes. Thermal analysis indicated increased stability, with a higher endothermic peak and an enthalpy increase from 6.885 J/g to 8.584 J/g. Antibacterial assays revealed strong efficacy against Escherichia coli and Staphylococcus aureus, reducing bacterial growth by over 90%. The enhanced hydrophobicity, mechanical strength, thermal stability, and antibacterial activity of PS/PCL/CO/NiO membranes make them highly promising for applications in tissue engineering, wound dressings, and water treatment.
Published Version
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