Collagen Hydrolysate Prepared from Chicken By-Product as a Functional Polymer in Cosmetic Formulation.

Pavel Mokrejš,Aneta Prokopová,Jana Pavlačková,Robert Gál

doi:10.3390/molecules26072021

Pavel Mokrejš, Aneta Prokopová + Show 2 more

Open Access

https://doi.org/10.3390/molecules26072021

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Abstract

Chicken stomachs can be processed into collagen hydrolysate usable in cosmetic products. The aim of the study was to verify the effects of a carbopol gel formulation enriched with 1.0% (w/w) chicken hydrolysate on the properties of the skin in the periorbital area after regular application twice a day for eight weeks in volunteers ageed 50 ± 9 years. Skin hydration, transepidermal water loss (TEWL), skin elasticity and skin relief were evaluated. Overall, skin hydration increased by 11.82% and 9.45%, TEWL decreased by 25.70% and 17.80% (always reported for the right and left area). Generally, there was an increase in skin elasticity, a decrease in skin roughness, as the resonance times decreased by 85%. The average reduction of wrinkles was 35.40% on the right and 41.20% on the left. For all results, it can be seen that the longer the cosmetic gel formulation is applied, the better the results. Due to the positive effect on the quality and functionality of the skin, it is possible to apply the cosmetic gel formulation in the periorbital area. The advantage of the product with chicken collagen hydrolysate is also the biocompatibility with the skin and the biodegradability of the formulation.

Highlights

Hydration values before application of the cosmetic gel formulation with chicken collagen hydrolysate indicate sufficiently moisturizued skin as the avarage values in volunteers were more than 45 c.u
The results showed that the cosmetic formulation with the highest percentage of cosmetic formulation, as the study shows that the concentration of collagen hydrolysate is collagen hydrolysate (10%) had the best effect on skin elasticity and on skin crucial when applying the cosmetic formulation to the skin [38]
Collagen hydrolysate was prepared from poultry stomachs by a biotechnological process and was blended in an amount of 1.0% (w/w) to the carbopol gel to prepare cosmetic gel formulation

Summary

Introduction

The waste contains a large amount of collagen, so the effort is to utilize these products for the production of collagen hydrolysates, which can be used in both the food (due to high nutritional value) and cosmetic industry (anti-aging creams) [2,3]. Molecular weight (Mw ) ranges usually from 0.5 to 15.0 kDa, the hydrolysates are non-toxic and dermatologically acceptable [5]. They are soluble in cold water, have surface-active properties and neutral pH with good biological properties [6]. With suitable processing of waste into hydrolysates and gelatins, their subsequent application in the food, pharmaceutical and cosmetic industries is possible

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