Abstract

We propose a new cold dialysate regeneration system that requires 10 L per treatment for home hemodialysis. In this system, by using cold dialysate and 2 activated carbon columns alternatively switched between adsorption and desorption. In animal experiments (n = 8, dogs) were conducted to validate the cold dialysate regeneration system. When it is used in a conventional hemodialysis, the urea reduction ration was 60.9 ± 6.3% and Kt/V was 1.0 ± 0.2. BUN concentration in the dialysate was 5.8 mg/dL and serum electrolytes remained stable. The proposed cold dialysate regeneration system using only a small volume of dialysate will be useful for home hemodialysis.

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