Abstract
ObjectivesOur study aimed to investigate the prevalence of cognitive impairment(CI) and the associated risk factors among elderly people in Shanghai urban area, China.MethodsA population-based survey was conducted among people aged 55 years or older in urban areas of Shanghai. Face-to-face interviews were carried out to collect information including demographic characteristics, medical history, and medication use, etc. The validated Chinese version of the Mini-Mental State Examination(MMSE) was used to screen subjects with CI, and the criteria of CI were adjusted for education levels.ResultsA total of 3,176 home-living residents (≥55 years old) were included in the study. Among them, 266 people (102 men and 164 women) were identified as cognition impaired, with a prevalence of 8.38% (266/3,176, 95% CI: (8.26, 8.49)) for both genders, 9.21% (102/1,107,95% CI: (9.18, 9.33)) for men and 7.93% (164/2,069, 95% CI: (7.80, 8.09)) for women, respectively. Furthermore, we found that several significant risk factors, including social factors(education, number of children, marriage status, and family structure), physiological factors (age, blood glucose level, and obesity), factors on living styles(physical exercise, diet & chronic diseases), and genetic factor(ApoE), associated with CI onset.ConclusionsThis study confirms the high prevalence of CI among the elderly population in the Shanghai urban in China, similar to previous epidemiologic studies in Western countries. The putative risk factors associated with CI merit further investigated.
Highlights
Numerous studies have shown that the prevalences of Alzheimer’s disease(AD) in China is comparable with the data in European and North American [1,2]
Pre-dementia sydromes comprised of different types of cognitive impairments (CI) are very worthwhile to assess the prevalence and incidence in populations
Prevalence of CI Among all the 3,176 participants with valid Mini-Mental State Examination (MMSE) scores, 266 (8.38%, 95CI:(8.26,8.49)) were diagnosed as cognitive impaired according to the pre-set diagnosing criteria
Summary
Numerous studies have shown that the prevalences of Alzheimer’s disease(AD) in China is comparable with the data in European and North American [1,2]. Pre-dementia sydromes comprised of different types of cognitive impairments (CI) are very worthwhile to assess the prevalence and incidence in populations. Only limited studies are conducted to examine the epidemiology of CI in China with the largest aging population so far. On the basis of our previous study for CI and associated factors among the elderly in the Shanghai suburb [7], we estimated the prevalence of CI as well as associated factors for CI among home-living population (≥55 years old) in urban areas of Shanghai, China
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