Abstract
Main observation and conclusion[Cp*Co(CO)I2] effectively catalyzes pyridyl‐directed C—H allylation of arenes with allylic amines in the presence of AgOAc and CF3COOAg. The reaction features ortho‐position monoallylation of 2‐pyridylarenes, giving the allylated arenes in moderate to high yields. A range of functional groups including OMe, Me, Ph, F, Cl, Br, CF3, C(O)Me, COOEt, and COOH groups are tolerated. Pyrimidyl‐directed C—H allylation of arenes were also performed under the same conditions. Reaction of 2‐phenylpyrimidine, 2‐(4‐methoxyphenyl)pyrimidine, and 2‐(3‐fluorophenyl)pyrimidine leads to a mixture of ortho‐position mono‐ and bisallylation products. Reaction of other 2‐(substituted aryl)pyrimidines resulted in ortho‐position monoallylation products.
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