Abstract
Organelle motility is essential for the functioning of the eukaryotic cell. Actively modifying intracellular structures allows cells to change and adapt to different conditions. In plants, reorganization of the chloroplasts is critical to adapt to changes in light quality and intensity. Our analysis of chloroplast motility in moss provides evidence that this active transport is facilitated by the microtubule cytoskeleton and molecular motors. We will present detailed in vivo measurements of organelle organization and motility, combined with coarse-grained mesoscale modeling. Our simulations take into account both thermal fluctuations and the topology of the microtubule network, and shed light into the molecular mechanisms at play.
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