Abstract
Coronavirus disease 2019 (COVID-19) is already well known globally1 . The Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 infection) causes a spectrum of severe clinical manifestations, which leads to a high rate of intensive care unit (ICU) admissions and mortality. We report a first case of COVID-19 with reactivation of human herpesvirus (HHV) alpha subfamily (herpes simplex virus I [HSV Ⅰ] and varicella-zoster virus [VZV]). Due to the immunosuppressive state associated with COVID-19, infection of the HHV alpha subfamily (HSV Ⅰ and VZV) could be potentially life threatening.
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