Abstract
Hepatocellular carcinoma (HCC) represents the fourth most common cause of death from cancer. The etiologic agents responsible for the majority of HCC are the infections with hepatitis B and C viruses and ethanol abuse. Adenocarcinoma is the most frequent hystologic type. Surveillance is performed with provided evidence-base recommendations for identification of patients at risk. The clinical management choices for HCC are complex because of the numerous options that exist for treatment (excision, local ablation strategies, liver transplantation, radiation therapy, regional and systemic chemotherapy and novel agents as sorafenib) and the underlying liver disease that affects the majority of HCC patients.The cancer of the biliary tract includes the gallbladder and intrahepatic and extrahepatic bile ducts tumors. These cancers are, in general, rare and with overall poor prognosis. The management of patients with biliary tract cancer is complex and a dedicated, multidisciplinary team is necessary.
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