Abstract

Numerous diagnostic clues are used in routine dermatopathological diagnostics. Ideally, adiagnostic clue can lead directly to aspecific diagnosis and save further time-consuming additional diagnostic procedures. This article discusses the concept of "clues to diagnosis" starting from its historical beginnings with areview of relevant studies and including current literature. Selected clues to dermatophytosis, psoriasis, and mycosis fungoides are analyzed. In addition, some newer and still little-known dermatopathological clues to inflammatory and infectious skin disease are presented. The aim is to specify the use of clues on the basis of current findings and to draw attention to scientifically sound clues.

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