Abstract
Introduction: Antipsychotics are widely used in geriatric patients with various psychiatric disorders. A growing number of atypical anti-psychotics are currently available with various side effect profiles. These agents, while expanding clinical options, also raise concern. Many questions about the use of anti-psychotics in older patients remain unanswered by available clinical literature. Among the second generation anti-psychotics, clozapine is often one that is avoided the most due to its adverse side effect profile which includes agranulocytosis, requiring monthly monitoring of cell counts. However, in patients with refractory positive symptoms of schizophrenia, clozapine can be the drug of last resort. Such was the case with one of our patients.
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