Abstract
BackgroundLichenoid drug eruption is rare and can mimic idiopathic lichen planus and other dermatoses. Clonazepam, a commonly used drug for the treatment of anxiety-related disorders and seizures, is known to be an unlikely cause of cutaneous adverse effects. Only one case report of LDE due to clonazepam has been reported.Case presentationA 81-year-old male patient with Alzheimer’s disease developed a lichenoid eruption after taking clonazepam. He developed a violaceous scaly patch on his lower extremities, from both buttocks to the feet. The cutaneous eruption resolved 2 months after cessation of clonazepam and with initiation of corticosteroid therapy.ConclusionA skin eruption that develops after clonazepam administration can be a lichenoid drug eruption, which is less likely to resolve spontaneously and requires discontinuation of clonazepam administration.
Highlights
Lichenoid drug eruption is rare and can mimic idiopathic lichen planus and other dermatoses
In the current case report, we present an 81-year-old Alzheimer’s disease (AD) patient with Lichenoid drug eruption (LDE) induced by clonazepam
In the current case, LDE developed in patients with preexisting dermatitis after taking clonazepam, and it was improved over several months after cessation of the drug
Summary
Lichenoid drug eruption is rare and can mimic idiopathic lichen planus and other dermatoses. Clonazepam, a commonly used drug for the treatment of anxiety-related disorders and seizures, is known to be an unlikely cause of cutaneous adverse effects. Case presentation: A 81-year-old male patient with Alzheimer’s disease developed a lichenoid eruption after taking clonazepam. He developed a violaceous scaly patch on his lower extremities, from both buttocks to the feet. Lichenoid drug eruption (LDE) is a rare type of drug eruption that can resemble idiopathic lichen planus (LP) clinically and histopathologically. Clonazepam is one of the most commonly used drugs for treating anxiety-related disorders and seizures Common side effects such as drowsiness and sedation are well known and can be appropriately considered by clinicians. Rare hypersensitivity reactions and cutaneous adverse effects are difficult to consider in
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