Clinical-ophthalmic characteristics, differential diagnostic criteria for predicting endogenous uveitis in small domestic animals as a manifestation of paraneoplastic syndrome

Abstract

The reactive inflammatory process in the eye reflects a protective and adaptive reaction to the accumulation of toxins and under-oxidized products in the iris. Clinical signs depend on the degree of inflammation in the vascular tract, and the change in the eyes, expressed by a different picture, has a heterogeneous character. The paper presents the results of studies on the study of differential diagnostic clinical signs of destruction of the hemato-ophthalmic barrier as a manifestation of paraneoplastic syndrome. Substantiated clinical risk factors and diagnostic criteria. It is shown that the clinical manifestation of endogenous uveitis in small domestic animals is diverse and does not fit into the classical concepts of clinical forms of exogenous origin. Characteristic is the generalized nature of inflammation with lesions in dogs of the anterior uveal tract, in cats of the posterior uveal tract. Clinical forms of serous-fibrinous anterior uveitis in dogs and hemoragic chorioretinitis in cats in the presence of synechiae and mooring in the vitreous body are attributed to clinical risk factors for blindness in small pets. The schemes of hormonal and drug treatment and pathogenetic treatment have been developed. The treatment system provided for the choice of a regimen, the duration of treatment and an assessment of its effectiveness, taking into account not only clinical features, but also risk factors for the occurrence of the disease.