Abstract

Uremia not only involves the accumulation of small molecules of uremic solutes in plasma but also ecological dysregulation of the gut microbiota. At present, hemodialysis is the preferred method for clinical management of uremic patients to avoid complications such as intestinal diseases caused by intestinal flora disturbances. Herein, we have attempted to clarify the clinical value of probiotics in progressive nutritional support nursing for uremic hemodialysis patients. One hundred and thirty-six uremic patients undergoing hemodialysis in our hospital between October 2021 and October 2022 were divided into experimental and control groups. The control group underwent conventional nursing care, whereas the experimental group underwent progressive nutritional support nursing (intervention group). After intervention, the visual analogue scale scores of the EuroQoL-5 Dimension Questionnaire in the experimental group were elevated relative to those in the controls (P < 0.05). The health-related quality of life questions that included creatinine clearance rate, urea nitrogen clearance rate, body mass index, and albumin were higher in the experimental group than controls, whereas the white blood cell count in the experimental group was lower than controls (P < 0.05). Furthermore, the total complication rate in the experimental group was lower than the control group (P < 0.05). In summary, applying progressive nutritional support nursing to uremic patients can improve clinical indicators and reduce the incidence of complications.

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