Abstract
At present, conventional whole brain radiotherapy is the standard treatment for brain metastases and prophylactic cranial irradiation, and it can improve patients' clinical symptoms and survival. However, whole brain radiotherapy may induce cognitive function impairment and affect patients' long-term quality of life. The newest radiotherapy technology can protect the hippocampal gyrus during whole brain radiotherapy and then protect cognitive function and improve quality of life. This article reviews the methods and clinical value of hippocampal gyrus protection in whole brain radiotherapy, as well as related advances. Key words: Hippocampal sparing; Whole brain radiotherapy; Prophylactic cranial irradiation; Cognitive function; Progress
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