Abstract
To obtain preliminary data on personality and clinical/psychopathological predictors of combined use of psychoactive drugs in patients with psychostimulant dependence. Eighty-nine inpatients were examined. Family history of drug dependence, personality disorders, clinical/psychopathological characteristics and disease course (breakdowns, relapses, remissions) were compared in patients with psychostimulant dependence (n=35) and patients who used other psychoactive substances (n=54). Combined use of psychoactive substances is predicted by a complex of factors, including genetic, biological (neurochemical), psychological (personality characteristics of comorbidity and social influences). Based on their proportion, three types of psychostimulant dependence were determined.
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