Clinical study of mecobalamin combined with ganglioside in the treatment of chronic alcoholic peripheral neuropathy

Abstract

Objective To analyze the clinical effect of mecobalamin combined with ganglioside on chronic alcoholic peripheral neuropathy. Methods Eighty-four cases of chronic alcohol peripheral neuropathy were selected as the subjects of this study, according to the different treatment methods, they were divided into the observation group (treated with mecobalamin combined with ganglioside) and control group (only treated with mecobalamin), each group of 42 patients, Eighty-four patients were voluntarily involved in this study. The total effective rate of treatment, the nerve conduction velocity before and after treatment, the incidence of adverse reactions, and the satisfaction of treatment were recorded and compared in the two groups. Results In the observation group, the total effective rate was significantly higher than that of the control group (P 0.05), after treatment, the nerve conduction velocity in observation group were significantly better than that of the control group (P 0.05); the treatment satisfaction was (95.23±2.11) points in the observation group, and the treatment satisfaction was (75.23±4.14) in the control group, the difference was significant (P<0.05). Conclusions Chronic alcoholic peripheral neuropathy patients using mecobalamin combined with ganglioside treatment, can significantly improve the total efficiency of treatment, the safety of drug use is guaranteed, nerve conduction velocity were optimized, which can quickly return to normal life, patients with a high degree of satisfaction, it is worthy of clinical application. Key words: Nerve conduction velocity; Mecobalamin; Ganglioside; Chronic alcoholic peripheral neuropathy