Abstract
Background To investigate the efficacy and safety of MEBO combined with Jinhuang powder for the treatment of diabetic foot with infection. Methods From August 2015 to August 2019, patients with diabetic foot in our hospital were divided into the treatment group and control group. The treatment group was treated with moist exposed burn ointment (MEBO) combined with Jinhuang powder, while the control group was treated with MEBO only. Results After one week of treatment, the effective rate in the treatment group was 100%, and the effective rate in the control group was only 76%. The difference between the two groups was statistically significant (P < 0.05). The wound pain score was 2.40 ± 1.38 in the treatment group and 3.76 ± 1.85 in the control group. The difference was statistically significant (P < 0.01). After one month of treatment, the effective rate of wound healing was 92.0% in the treatment group and 68% in the control group. The difference between the two groups was statistically significant (P < 0.05). Conclusion MEBO combined with Jinhuang powder is effective in treating diabetic foot with infection wound.
Highlights
Diabetes is a group of metabolic diseases characterized by chronic hyperglycemia
It will be difficult to control effectively due to the blood supply disorder of the distal limb. e amputation rate of patients with clinical diabetic foot infection was higher than that of patients without infection, and about 80%–85% of diabetic foot patients were forced to choose amputation [4,5,6,7]
Modern medicine has confirmed that the topical use of the drug can reduce the proportion of leukocytes and neutrophils in peripheral blood, reduce the permeability of blood vessels, and have antiswelling and anti-inflammatory effects. It can improve local blood circulation, effectively control infections, and significantly improve curative effects [9]. erefore, we speculate that the combined use of moist exposed burn ointment (MEBO) and Jinhuang powder has a better effect on wound healing, but the curative effect of MEBO and Jinhuang powder on wound healing has not been reported
Summary
To investigate the efficacy and safety of MEBO combined with Jinhuang powder for the treatment of diabetic foot with infection. From August 2015 to August 2019, patients with diabetic foot in our hospital were divided into the treatment group and control group. E treatment group was treated with moist exposed burn ointment (MEBO) combined with Jinhuang powder, while the control group was treated with MEBO only. E difference was statistically significant (P < 0.01). After one month of treatment, the effective rate of wound healing was 92.0% in the treatment group and 68% in the control group. E difference between the two groups was statistically significant (P < 0.05). MEBO combined with Jinhuang powder is effective in treating diabetic foot with infection wound
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