Clinical study in treatment of chronic cor pulmonale heart failure with danhong injection and dobutamine

Abstract

Objective To explore the clinical curative effect of danhong injection and dobutamine in chronic cor pulmonale(i.e.cor pulmonale)heart failure(HF). Methods 86 patients with chronic pulmonary heart disease complicated with heart failure were randomly divided into the observation group (n=46) and the control group (n=46). Two groups were treated with oxygen, anti-inflammatory, diuretics and vasodilators, correction of acid-base balance and water electrolyte disorders and other conventional treatment, the observation group and Danhong injection combined with dobutamine treatment, compared two groups of patients. Results The treatment group compared with the comparison group, after treatment heart rate, respiratory rate, arterial blood carbon dioxide partial pressure, high shear viscosity, low shear viscosity, reduced viscosity, plasma viscosity, fibrinogen reduce obviously.arterial oxygen saturation, arterial oxygen partial pressure, ejection fraction obvious rise, NYHA heart function graduation change for the better, the differences are statistically significant (P<0.05). The total effective rate in the treatment group 91.3%(42/46) with the comparison group 75.0% (30/40) compared to significantly (P<0.05). Conclusion Danhong injection and dobutamine treats cor pulmonale HF to have safely reliable, effective quick, the treatment course short, the poisonous side effect small and so on many merits, is worth the clinical promoted application. Key words: Danhong injection; Dobutamine; Chronic cor pulmonale; Heart failure