Abstract
Objective To investigate clinical significant and changes of brain tissue partial pressure of oxygen (Pbt O2 ) in the course of mild hypothermia treatment (MHT) of severe traumatic brain injury (sTBI).Methods There were 38 sTBI cases with mild hypothermia treatment in the course.Pbt O2,intracranial pressure (ICP),jugularn venous oxygen saturation (SjvO2 ),and cerebral perfusion pressure (CPP) were continuously monitored for analyzing the correlations insides,and clinical outcomes were valued using the Glasgow Outcome Scale score (GOSs).Results Of 38 patients with sTBI,increasing PbtO2,Sjv O2,CPP and decreasing ICP were found obviously from the begin of MHT. There was negative linear correlation between PbtO2 and ICP.Otherwise,there was positive linear correlation between PbtO2 and SjvO2.Monitoring process which CPP and Sjv O2 levels were under normal circumstances,there were still a large proportion of patients with low PbtO2 situation after MHT.Conclusions Continuous monitoring of PbtO2 can reflect the condition of regional cerebral oxygen metabolism and guide treatment and predicting outcome. Key words: Traumatic brain injury; Mild hypothermia; Brain tissue partial pressure of oxygen
Published Version
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