Clinical significance of the concentration of D-D,hs-CRP in serum of the young patients with acute progressive cerebral infarction before and after the proceeding and treatment

Abstract

Objective To study the correlation between the levels of D-Dimer(D-D),high sensitive C-reactive protein(hs-CRP) in serum of the young patients with acute progressive cerebral infarction before and after the proceeding and treatment. Methods Levels of hs-CRP, D-D were detected respectively in serum of the 20 young patients with acute progressive cerebral infarction, the 30 young patients with acute non- progressive cerebral infarction and 50 healthy people sampled as control group and correlation were analysed before and after the proceeding and treatment. Results Compared with healthy person and young patients with non-progressive cerebral infarction, the levels of D-D and hs-CRP in serum of young patients with progressive cerebral infarction were significantly higher (P＜0.01). The level of D-D was positively correlated with that of hs-CRP,The levels of D-D and hs-CRP in serum of patients with cerebral infarction were significantly lower than before after having been treated and intervented effectively. Conclusions The levels of D-D,hs-CRP are closely related to the existence and development of the young patients with cerebral infarction. The levels of D-D and hs-CRP can be used as one of the assessment indexes of the young patient's conditions and is helpful for clinic forecast and intervention of acute progressive cerebral infarction. Key words: Youth ; Progressive ; Cerebral infarction ; D-Dimer ; High sensitive C-reactive protein ;