Abstract
Background: Carcinoma of the stomach remains a significant cause of cancer-related mortality worldwide, often presenting with non-specific symptoms such as epigastric pain, weight loss, nausea, and anemia. The clinical presentation frequently correlates with the disease stage at diagnosis, influencing treatment outcomes. This study aimed to evaluate the clinical presentation of gastric carcinoma and its relationship to treatment outcomes. Methods: This was a prospective observational study that was conducted in the Department of Surgery, Shaheed Ziaur Rahman Medical College Hospital, Bogura, Bangladesh from January 2007 to January 2009. A total of 50 patients with carcinoma of the stomach were selected irrespective of age and gender purposively. Data were analyzed using MS Office tools. Results: Significant clinical features included anemia (80%), epigastric tenderness (70%), and palpable lumps (60%). Gastroduodenoscopy detected 74% antral lesions with 95.6% sensitivity. Patients with vague abdominal symptoms presented at advanced stages, while general symptoms correlated with early stages. Curative resections achieved recurrence-free survival in 52% at 24 months. Palliative procedures were common (50%), and non-compliance (16%) negatively impacted outcomes. Adjuvant chemotherapy improved survival for 80% of cases. Conclusion: Anemia, epigastric tenderness, and lumps are key features of stomach cancer. Advanced stages show vague symptoms; early stages show general symptoms. Gastroduodenoscopy aids diagnosis. Early detection, regular follow-ups, and routine gastroduodenoscopy improve outcomes and survival rates.
Published Version
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