Abstract
Although blastocyst vitrification is commonplace among IVF clinics, the need for a closed, easy-to-learn and use system remains. Using a DMSO-free system will help avoid possible cryoprotectant toxicity. Micro-volume containers and rapid procedure times remain technically challenging for some embryologists. The I.C.E. vitrification system relies on a relaxed protocol, closed device, and vitrification regime that is closer to equilibrium vitrification, and does not depend on ultra fast cooling rates and small volumes.
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