Clinical pathology conference case #6: multiple tumors of the skull in a pediatric patient

Abstract

A 2-year-old female from Guatemala presented with multiple tumors affecting the skull, orbits, and the maxillary sinuses. Clinical examination revealed bilateral exophthalmos and marked periorbital swelling in the left eye that was displaced inferiorly. Additionally, the patient had slight hyperpigmentation associated with the periorbital swellings, and temporal swelling was also present. Bleeding from the right nostril, clear fluid dripping from the left nostril, and mouth breathing were present.