Abstract
Background: The objectives of this study were to evaluate the effectiveness, the patients compliance and tolerability to bacillus Calmette-Guerin (BCG) intravesical instillation after transurethral resection of bladder tumor (TURBT) for stage Ta–T1, grade G1–G3 transitional cell carcinoma (TCC) of the urinary bladder. Methods: Between January 1995 and May 2002, 127 patients (110 males and 17 females) aged between 40 and 81 years 66.5±8.4 years) with Ta–T1, G1–G3 TCC of the urinary bladder were treated by TURBT and adjuvant intravesical instillation with BCG. The following details were recorded and evaluated: the disease-free survival rates, the tumor recurrence, age, gender, morphology, the size and number of tumors and side effects of BCG instillation. Results: 80 (63%) and 47 patients (37%) initially presented with multifocality and monofocality, respectively, were analyzed. Follow-up periods were 3–48 months (median, 18 months) for 110 of the 127 patients enrolled. At 3 months follow up, 40 multifocali...
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