Abstract

Objective To evaluate the clinical efficacy of compound Danshen and Cerebrolysin Vial combination therapy in treating cases of neonatal hypoxic ischemic encephalopathy(HIE).Methods 90 cases of neonatal HIE hospitalized form May 2005 to September 2006 were randomly separated into an experiment group and a control group.On the basis of conventional trigeminal supporting treatment,the experiment group was treated with additional compound Danshen and Cerebrolysin Vial combination therapy.At the end of therapeutic courses,overall effective rate was evaluated.Results The overall effective rate of the experiment group was 95.56%,comparing with a 77.78% overall effective rate in the control group.The overall effective rate of the experiment group was significantly different from the control group (P<0.05).Conclusions Compound Danshen and Cerebrolysin Vial combination therapy was significantly effective in treating neonatal hypoxic ischemic encephalopathy.This therapy is recommendable in daily clinical treatment of HIE. Key words: Compound Danshen; Cerebrolysin Vial; Hypoxic ischemic encephalopathy; Neonate

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