Clinical observation of trabeculectomy combined with amniotic membrane transplantation in glaucoma filtering surgery

Abstract

Objective To observe the application of biological amniotic membrane in glaucoma filtration surgery. Methods Choose from March 2011 to March 2015, 78 patients (92 eyes) of angle closure glaucoma were treated in Shanghai Baoshan District traditional Chinese and Western medicine hospital, performed a retrospective analysis. All patients were randomly divided into 3 groups, underwent trabeculectomy in patients of 1 group, underwent trabeculectomy combined with amniotic membrane transplantation in patients of 2 groups, including group one of patients placed in the amniotic membrane under the scleral flap, group two were placed in the amniotic membrane under conjunctiva. All the operations were performed by the author, visual acuity, intraocular pressure, follicles, anterior chamber and complications were observed every day for one week after operation. After operation 6 months, the long diameter, and width diameter of the filtration bubble were measured by UBM. To compare the clinical effects of three surgical procedures. Results The best corrected visual acuity of the three groups before and after the operation was improved significantly, the difference was statistically significant (u=-4.99, P 0.05). In the 2 groups, the time of local filtration and vesicle congestion was higher than that of the other two groups, and the filtering blebs were relatively flat. Three eyes with bleb length and width were compared, the difference was statistically significant (F=104.66, 20.40; P 0.05). Conclusion Trabeculectomy combined with amniotic membrane transplantation is an effective method for the treatment of angle closure glaucoma. It has a high rate of operation, a marked decrease in the scarring of the filtering canal, and the formation of functional filtering blebs. Key words: Glaucoma; Trabeculectomy; Biological amniotic membrane transplantation