Abstract

目的 探讨进一步提高中晚期声门型喉癌患者生存率及生存质量的方法.方法回顾分析53例声门型喉鳞状细胞癌实施喉癌甲状软骨窗式切除带蒂肌瓣修复喉腔术临床资料,其中,T2N036例,T2N13例,T3N012例,T3N12例.临床分期,Ⅱ期36例,Ⅲ期17例.使用电刀结合电锯行喉腔肿瘤、甲状软骨窗式切除术,把制备的肌瓣通过开窗口修复喉腔.单蒂肌瓣修复:胸骨舌骨肌26例,带舌骨、胸骨舌骨肌9例,肩胛舌骨肌5例,双侧肩胛舌骨肌修复喉腔8例.双蒂肌膜肌瓣修复:胸骨舌骨肌4例.Kaplan-Meier计算生存率及肿瘤复发趋势.结果 3、5年生存率分别为91.9%和84.2%,肿瘤复发5例(T2No 3例,T3N01例,T3N01例),肿瘤复发率为11.0%.拔管率为96.2%(51/53),拔管时间为2~4周.发音成功率为100%.结论采用喉癌甲状软骨窗式切除带蒂肌瓣修复喉腔术,基本保留了喉腔的生理形态,修复组织稳定,有利于发音,提高了生存质量。

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